As Monk and his friends watch a TV newsmagazine piece on the solution of his hundredth case, he realizes that one of the victims was murdered by a different killer.

Monk develops a crush on a model who is accused of murder. Despite the overwhelming evidence (including her confession), Monk is determined to prove her innocence.

Monk finds himself forced to move into what he hopes will be his dream house… which is anything but.

Stottlemeyer must keep up the pretense that Monk is dead, while Adrian tries to determine who framed him for murder.

Monk, Sharona, Lt.Disher and Stottlemeyer go to New York City to follow the leads concerning Trudy’s murder which was given by Dale the Whale. However, three people were killed, including the Latvian ambassador to the United Nations when Monk and the rest were checking into their hotel.